SCHEMBL580342

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Amg-900 SCHEMBL29479191	0.89	AURKA (1.00)	AURKAAURKBULK1RPS6KA5RPS6KA4
	Amg-900 SCHEMBL29351414	0.89	AURKA (1.00)	AURKAAURKBULK1RPS6KA5RPS6KA4
	Amg-900 SCHEMBL503564	0.89	AURKA (1.00)	AURKAAURKBULK1RPS6KA5RPS6KA4
	SCHEMBL580354	0.84	AURKA (0.84)	AURKAAURKBULK1RPS6KA5RPS6KA4
	SCHEMBL581417	0.83	AURKA (0.60)	AURKAAURKBULK1RPS6KA5RPS6KA4
	SCHEMBL581178	0.82	AURKB (0.84)	AURKAAURKBULK1RPS6KA5RPS6KA4
	SCHEMBL16290183	0.82	AURKA (0.81)	AURKAAURKBULK1RPS6KA5RPS6KA4
	SCHEMBL581139	0.80	AURKA (0.57)	AURKAAURKBULK1RPS6KA5RPS6KA4
	SCHEMBL581542	0.80	AURKA (0.82)	AURKAAURKBULK1RPS6KA5RPS6KA4
	SCHEMBL17460752	0.80	AURKA (0.72)	AURKAAURKBULK1RPS6KA5RPS6KA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.