Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 19/20 | 0.81 |
| ▸ | MAPK9 | P45984 | 13/20 | 0.81 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.81 |
| ▸ | RPS27 | P42677 | 5/20 | 0.81 |
| ▸ | PRKD2 | Q9BZL6 | 6/20 | 0.68 |
| ▸ | CSF1R | P07333 | 5/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.68 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.68 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.68 |
| ▸ | AKT1 | P31749 | 3/20 | 0.67 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.67 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.67 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.67 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.64 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.64 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.64 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.64 |
| ▸ | BLK | P51451 | 1/20 | 0.64 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13514275 | 0.93 | MAPK8 (0.77) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514290 | 0.91 | MAPK8 (0.81) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514089 | 0.90 | MAPK8 (0.66) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL1145860 | 0.90 | MAPK8 (1.00) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514401 | 0.89 | MAPK8 (0.83) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL1145506 | 0.88 | MAPK8 (0.83) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514141 | 0.87 | MAPK8 (0.68) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514405 | 0.87 | MAPK8 (0.73) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514093 | 0.86 | MAPK8 (0.70) | MAPK8MAPK9MAPK10RPS27PRKD2 | |
| SCHEMBL13514161 | 0.86 | MAPK8 (0.64) | MAPK8MAPK9MAPK10RPS27PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006083673-A2 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES | ABBOTT LABORATORIES (US) | 2006-08-10 | — | — | WO | claimed |