Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555859 | 0.83 | GFER (0.50) | UBE2NTSHRMAPTMEN1KMT2A | |
| SCHEMBL3824049 | 0.79 | TSHR (0.47) | UBE2NTSHRLMNAHTTNPSR1 | |
| SCHEMBL7753447 | 0.78 | TSHR (0.48) | UBE2NTSHRMAPTMEN1KMT2A | |
| SCHEMBL3829478 | 0.78 | TSHR (0.50) | UBE2NTSHRLMNAHTTNPSR1 | |
| SCHEMBL5935599 | 0.77 | MEN1 (0.57) | TSHRLMNAMAPTMEN1KMT2A | |
| SCHEMBL5807356 | 0.76 | TSHR (0.48) | UBE2NTSHRMAPTMEN1KMT2A | |
| SCHEMBL6555630 | 0.76 | PPARG (0.69) | ADRA1A | |
| SCHEMBL5935688 | 0.76 | GFER (0.49) | UBE2NTSHRMAPTMEN1KMT2A | |
| SCHEMBL5935593 | 0.75 | MEN1 (0.55) | TSHRLMNAMAPTMEN1KMT2A | |
| SCHEMBL5803860 | 0.75 | MEN1 (0.57) | TSHRLMNAHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | disclosed |