Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803612 | 0.89 | PPARG (0.52) | PPARGCYP3A4RXRAPPARALMNA | |
| SCHEMBL5803154 | 0.88 | PPARG (0.52) | PPARGCYP3A4RXRAPPARALMNA | |
| SCHEMBL1199905 | 0.82 | PPARG (0.51) | PPARGCYP3A4RXRAPPARALMNA | |
| SCHEMBL1201520 | 0.82 | PPARG (0.51) | PPARGCYP3A4RXRAPPARALMNA | |
| SCHEMBL5802960 | 0.81 | PPARG (0.51) | PPARGCYP3A4RXRAPPARALMNA | |
| SCHEMBL5803726 | 0.80 | PPARG (0.50) | PPARGCYP3A4RXRAPPARAL3MBTL1 | |
| SCHEMBL2007617 | 0.79 | FFAR1 (0.56) | PPARGCYP3A4RXRALMNAL3MBTL1 | |
| SCHEMBL943063 | 0.78 | PPARG (0.58) | PPARGCYP3A4RXRAPOLB | |
| SCHEMBL4874828 | 0.78 | PPARG (0.58) | PPARGCYP3A4RXRAPPARALMNA | |
| SCHEMBL3313236 | 0.78 | PPARG (0.58) | PPARGCYP3A4RXRAPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | claimed |
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | disclosed |