⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870993 | 0.85 | GRM5 (0.68) | — | |
| SCHEMBL1159521 | 0.77 | GRM5 (0.50) | — | |
| SCHEMBL16116343 | 0.76 | — | — | |
| SCHEMBL28748970 | 0.76 | — | — | |
| SCHEMBL19778794 | 0.76 | — | — | |
| SCHEMBL13726266 | 0.76 | GRM5 (0.48) | — | |
| SCHEMBL4860769 | 0.76 | GRM5 (0.48) | — | |
| SCHEMBL12394778 | 0.76 | GRM5 (0.48) | — | |
| SCHEMBL9906389 | 0.76 | — | — | |
| SCHEMBL15870897 | 0.73 | GRM5 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271944-A1 | 1-(2-(4-CYCLOPROPYL-1H-1,2,3-TRIAZOL-1-YL)ACETYL)-4-HYDROXYPYRROLIDINE-2-CARBOXA|MIDE DERIVATIVES AS VHL INHIBITORS FOR THE TREATMENT OF ANEMIA | GENENTECH, INC. (US) | 2023-08-31 | — | — | US | disclosed |
| US-9637477-B2 | Therapeutic substituted pyrroles | ALLERGAN, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-20150336940-A1 | THERAPEUTIC SUBSTITUTED PYRROLES | ALLERGAN, INC. | 2015-11-26 | — | — | US | disclosed |
| US-20150340612-A1 | UV EMITTERS COMPRISING A MULTIPLE BOND | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150340612-A1 | UV EMITTERS COMPRISING A MULTIPLE BOND | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| WO-2014106520-A1 | UV EMITTERS COMPRISING A MULTIPLE BOND | MERCK PATENT GMBH (DE) | 2014-07-10 | — | — | WO | disclosed |
| US-8252883-B2 | Silicon cluster substituted with a conductive organic material; thin film transistor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-08-28 | — | — | US | disclosed |
| US-8252883-B2 | Silicon cluster substituted with a conductive organic material; thin film transistor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-08-28 | — | — | US | disclosed |
| US-20110031487-A1 | COMPOUND FOR ORGANIC THIN-FILM TRANSISTOR AND ORGANIC THIN-FILM TRANSISTOR USING THE COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| US-20080206479-A1 | Organosilicon nanocluster, method of preparing the same and method of forming thin film using the same | SAMSUNG ELECTRONICS CO., LTD | 2008-08-28 | — | — | US | disclosed |
| US-20080206479-A1 | Organosilicon nanocluster, method of preparing the same and method of forming thin film using the same | SAMSUNG ELECTRONICS CO., LTD | 2008-08-28 | — | — | US | disclosed |
| WO-2006092268-A1 | BICYCLIC FIVE-MEMBERED HETEROARYL DERIVATIVES AND THEIR USE AS RENIN INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-09-08 | — | — | WO | disclosed |