Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 12/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669016 | 0.92 | PDE2A (0.35) | PDE2ATSHRGLANPSR1ALDH1A1 | |
| SCHEMBL23943802 | 0.90 | PDE2A (0.34) | PDE2ATSHRGLANPSR1ALDH1A1 | |
| SCHEMBL4665963 | 0.90 | PDE2A (0.34) | PDE2ATSHRGLANPSR1ALDH1A1 | |
| SCHEMBL23943801 | 0.89 | PDE2A (0.36) | PDE2ATSHRGLANPSR1ALDH1A1 | |
| SCHEMBL22818585 | 0.88 | PDE2A (0.33) | PDE2ATSHRGLANPSR1ALDH1A1 | |
| SCHEMBL22800685 | 0.88 | PDE2A (0.33) | PDE2ATSHRGLANPSR1ALDH1A1 | |
| SCHEMBL22800687 | 0.88 | PDE2A (0.33) | PDE2ATSHRGLANPSR1ALDH1A1 | |
| SCHEMBL22800686 | 0.88 | PDE2A (0.33) | PDE2ATSHRGLANPSR1ALDH1A1 | |
| SCHEMBL4666594 | 0.81 | TSHR (0.37) | PDE2ATSHRGLANPSR1ALDH1A1 | |
| SCHEMBL4666650 | 0.80 | PDE2A (0.36) | PDE2ATSHRALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100037-A1 | TRIAZOLOPYRIMIDINE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-09-28 | — | — | WO | disclosed |