Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.43 |
| ▸ | FNTB | P49356 | 7/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502482 | 0.84 | FNTA (0.52) | FNTAFNTBMAPK1DPP8SLC6A7 | |
| SCHEMBL3499758 | 0.83 | FNTA (0.44) | FNTAFNTBPRKAA2 | |
| SCHEMBL3501527 | 0.82 | FNTA (0.49) | FNTAFNTBCDK4CCND1DPP8 | |
| SCHEMBL3499833 | 0.82 | FNTA (0.49) | FNTAFNTBSLC6A7GRM5MEN1 | |
| SCHEMBL6634090 | 0.82 | FNTA (0.53) | FNTAFNTBMAPK1KMT2AALDH1A1 | |
| SCHEMBL3502028 | 0.81 | FNTA (0.48) | FNTAFNTBSLC6A7GRM5MEN1 | |
| SCHEMBL3497891 | 0.80 | FNTA (0.53) | FNTAFNTBCDK4CCND1ABL1 | |
| SCHEMBL3502156 | 0.80 | FNTA (0.49) | FNTAFNTBSLC6A7ABL1 | |
| SCHEMBL3499967 | 0.80 | FNTA (0.52) | FNTAFNTBMAPK1GRM5MEN1 | |
| SCHEMBL8052009 | 0.79 | FNTA (0.45) | FNTAFNTBDPP8SLC6A7GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005089515-A9 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | BRIGHAM & WOMENS HOSPITAL (US) | 2006-01-26 | — | — | WO | disclosed |