Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | HMGCR | P04035 | 5/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | RHOC | P08134 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804849 | 0.96 | SLCO1B1 (0.45) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL4169210 | 0.93 | HMGCR (0.47) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL5807727 | 0.92 | HMGCR (0.46) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL5805034 | 0.88 | MAPK14 (0.44) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL5805346 | 0.87 | HMGCR (0.43) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL5806553 | 0.87 | HMGCR (0.43) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL5805083 | 0.86 | EGFR (0.47) | MEN1POLBKMT2ATDP1MAPT | |
| SCHEMBL5804980 | 0.85 | ATR (0.45) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL5808829 | 0.82 | NPC1 (0.41) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL5804950 | 0.82 | KDR (0.42) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | claimed |