Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.75 |
| ▸ | TP53 | P04637 | 4/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | CCR1 | P32246 | 2/20 | 0.72 |
| ▸ | CCR5 | P51681 | 2/20 | 0.72 |
| ▸ | CCR8 | P51685 | 2/20 | 0.72 |
| ▸ | METAP1 | P53582 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.72 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.72 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268013 | 1.00 | KDM4E (0.75) | KDM4ETP53TDP1LMNACCR1 | |
| Hydrochloric Acid SCHEMBL28577751 | 0.97 | KDM4E (0.71) | KDM4ETP53TDP1LMNACCR1 | |
| SCHEMBL1397375 | 0.87 | KDM4E (0.58) | KDM4ETP53TDP1LMNACCR1 | |
| SCHEMBL30694104 | 0.86 | TP53 (1.00) | KDM4ETP53TDP1LMNACCR1 | |
| SCHEMBL29354466 | 0.86 | KDM4E (1.00) | KDM4ETP53TDP1LMNACCR1 | |
| SCHEMBL2852298 | 0.86 | TP53 (1.00) | KDM4ETP53TDP1LMNACCR1 | |
| SCHEMBL322756 | 0.86 | KDM4E (1.00) | KDM4ETP53TDP1LMNACCR1 | |
| SCHEMBL29767699 | 0.86 | TP53 (1.00) | KDM4ETP53TDP1LMNACCR1 | |
| SCHEMBL21315705 | 0.85 | KDM4E (0.55) | KDM4ETP53TDP1LMNACCR1 | |
| SCHEMBL131504 | 0.85 | KDM4E (0.62) | KDM4ETP53TDP1LMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 794 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240349602-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-10-17 | — | — | US | claimed |
| CN-115093396-B | Pyridinylether compound containing pyrimidamine and preparation method and application thereof | 湖南化工研究院有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-112204765-A | Photoelectric conversion element and method for manufacturing photoelectric conversion element | 索尼公司 | 2021-01-08 | — | — | CN | claimed |
| CN-105541795-B | Pyridyl-pyrimidine class compound and its synthetic method and application | 南京林业大学 | 2018-01-19 | — | — | CN | claimed |
| CN-107434801-A | A kind of 4 ' pyridyl-pyrimidine class compounds and its synthetic method and application | 南京林业大学 | 2017-12-05 | — | — | CN | claimed |
| CN-105541795-A | Pyridyl pyrimidine compound and synthesizing method and application thereof | UNIV NANJING FORESTRY | 2016-05-04 | — | — | CN | claimed |
| US-9156843-B2 | Organic electroluminescent device comprising an organic layer containing an indolocarbazole compound | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2015-10-13 | — | — | US | claimed |
| CN-102432634-A | 2-amino-4- (2' -pyridine) -pyrimidine diperoxovanadium ammonium salt complex and single crystal culture and application thereof | UNIV HENAN SCIENCE & TECH | 2012-05-02 | — | — | CN | claimed |
| CN-102391304-A | 4-(2'-pyridine)-pyrimidine diperoxovanadate ammonium salt coordination compound and single crystal culture method and application thereof | UNIV HENAN SCIENCE & TECH | 2012-03-28 | — | — | CN | claimed |
| US-20110144140-A1 | PYRIDINYL-PYRIMIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2011-06-16 | — | — | US | claimed |
| EP-0431424-A2 | Pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | claimed |
| EP-0234104-B1 | NOVEL PYRIDINYLPYRIMIDINE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND A PLANT DISEASE PROTECTANT CONTAINING THEM AS THE ACTIVE INGREDIENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-10-24 | — | — | EP | claimed |
| US-4927827-A | Pyridinylpyrimidine derivatives, method for production thereof and a fungicide containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-22 | — | — | US | claimed |
| US-4873248-A | Pyridinylpyrimidines having fungicidal activity | SUMITOMO CHEMICAL CO., LTD. (JP) | 1989-10-10 | — | — | US | claimed |
| US-4783466-A | Novel pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-08 | — | — | US | claimed |
| US-4769376-A | Certain tri- or tetra-substituted pyridyl-1,2,4-triazoles useful as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-06 | — | — | US | claimed |
| US-4752608-A | Fungicidal pyridinylpyrimidine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-21 | — | — | US | claimed |
| EP-0270362-A2 | Pyridinylpyrimidine derivatives, method for production thereof and a fungicide containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-08 | — | — | EP | claimed |
| EP-0259139-A2 | Pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-09 | — | — | EP | claimed |
| EP-0234104-A2 | Novel pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144140-A1 | PYRIDINYL-PYRIMIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS | KCNJ2, KCNN2, KCNN1 | KDM4E 1122/4885TP53 4312/4885TDP1 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.