Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144157 | 0.87 | TLR7 (0.58) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL842632 | 0.87 | TLR7 (0.42) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL842116 | 0.84 | TLR7 (0.62) | TLR7TLR8NUDT1 | |
| SCHEMBL148087 | 0.84 | TLR7 (0.57) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL29551159 | 0.83 | TLR7 (0.54) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL147570 | 0.83 | TLR7 (0.54) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL20836817 | 0.83 | TLR7 (0.50) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL31379717 | 0.82 | TLR7 (0.53) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL144931 | 0.82 | TLR7 (0.53) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL12467809 | 0.82 | TLR7 (0.48) | TLR7TLR8LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006009832-A1 | SUBSTITUTED IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-01-26 | — | — | WO | disclosed |