Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300715 | 0.82 | TLR7 (0.34) | TLR7TLR8NUDT1 | |
| SCHEMBL4753608 | 0.76 | TLR8 (0.44) | TLR7TLR8NUDT1 | |
| SCHEMBL4753606 | 0.75 | TLR7 (0.46) | TLR7TLR8NUDT1 | |
| SCHEMBL22722043 | 0.72 | TLR7 (0.69) | TLR7TLR8NUDT1 | |
| SCHEMBL4303408 | 0.69 | TLR7 (0.40) | TLR7TLR8NUDT1 | |
| SCHEMBL5031367 | 0.68 | TLR8 (0.52) | TLR7TLR8NUDT1 | |
| SCHEMBL4393435 | 0.67 | TLR7 (0.58) | TLR7TLR8NUDT1 | |
| SCHEMBL31260417 | 0.67 | TLR8 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL4793617 | 0.66 | TLR8 (0.47) | TLR7TLR8 | |
| SCHEMBL1615363 | 0.66 | TLR8 (0.50) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006026760-A2 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |