Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755938 | 0.80 | TLR7 (0.51) | TLR8TLR7HTR2AHTR2BLMNA | |
| SCHEMBL10123111 | 0.72 | PRMT5 (0.50) | PRMT5TLR8TLR7HTR2AHTR2B | |
| Sotirimod SCHEMBL29395045 | 0.72 | TLR7 (0.50) | PRMT5TLR8TLR7HTR2AHTR2B | |
| Sotirimod SCHEMBL191424 | 0.72 | TLR7 (0.50) | PRMT5TLR8TLR7HTR2AHTR2B | |
| SCHEMBL4299811 | 0.72 | TLR7 (0.42) | PRMT5TLR8TLR7HTR2AHTR2B | |
| Epetirimod SCHEMBL29454521 | 0.70 | TLR7 (0.70) | PRMT5TLR8TLR7HTR2AHTR2B | |
| Epetirimod SCHEMBL29350668 | 0.70 | TLR7 (0.70) | PRMT5TLR8TLR7HTR2AHTR2B | |
| Epetirimod SCHEMBL544542 | 0.70 | TLR7 (0.70) | PRMT5TLR8TLR7HTR2AHTR2B | |
| SCHEMBL193507 | 0.70 | TLR7 (0.49) | PRMT5TLR8TLR7HTR2AHTR2B | |
| SCHEMBL5130116 | 0.70 | TLR7 (0.48) | PRMT5TLR8TLR7HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006026760-A2 | 1-AMINO IMIDAZO-CONTAINING COMPOUNDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |