SCHEMBL5809074

SCHEMBL5809074

CCCn1c(C)c(C)c2ccnc(OCc3ccc(F)cc3)c21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
CNR1 P21554 2/20 0.37
CNR2 P34972 2/20 0.37
DYRK1A Q13627 1/20 0.35
TSHR P16473 1/20 0.35
MAPK14 Q16539 1/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 1/20 0.34
MPO P05164 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MCHR1 Q99705 2/20 0.34
KDM5A P29375 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM5B Q9UGL1 2/20 0.33
MEN1 O00255 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5808769 0.99 CYP1A2 (0.48) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Phosphoric Acid SCHEMBL5806660 0.94 CYP1A2 (0.45) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Sulfuric Acid SCHEMBL5809225 0.94 CYP1A2 (0.45) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5806057 0.93 CYP1A2 (0.44) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Nitric Acid SCHEMBL5805971 0.92 CYP1A2 (0.43) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Trifluoroacetic Acid SCHEMBL5805692 0.91 CYP1A2 (0.43) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5806790 0.90 CYP1A2 (0.51) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5809447 0.89 CYP1A2 (0.50) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5806330 0.88 CYP1A2 (0.39) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5809961 0.88 CYP1A2 (0.48) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed