Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.49 |
| ▸ | HMGCR | P04035 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | RHOC | P08134 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14026658 | 0.87 | SLCO1B1 (0.52) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 | |
| SCHEMBL6871693 | 0.86 | HMGCR (0.64) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 | |
| SCHEMBL23651705 | 0.81 | HMGCR (0.58) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 | |
| SCHEMBL21637568 | 0.80 | SLCO1B1 (0.52) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 | |
| SCHEMBL5805357 | 0.80 | SLCO1B1 (0.51) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 | |
| SCHEMBL5805221 | 0.78 | HMGCR (0.65) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 | |
| SCHEMBL5808259 | 0.78 | SLCO1B1 (0.49) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 | |
| SCHEMBL5805022 | 0.76 | SLCO1B1 (0.57) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 | |
| SCHEMBL5823002 | 0.75 | HMGCR (0.56) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 | |
| SCHEMBL21637575 | 0.74 | HMGCR (0.61) | SLCO1B1ABCB11HMGCRHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |