Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 19/20 | 0.63 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263071 | 1.00 | TACR2 (0.63) | TACR2TACR1MCHR1 | |
| Acetic Acid SCHEMBL5013598 | 0.98 | TACR2 (0.63) | TACR2TACR1 | |
| SCHEMBL4262600 | 0.91 | TACR2 (0.66) | TACR2 | |
| SCHEMBL5800848 | 0.91 | TACR2 (0.66) | TACR2 | |
| SCHEMBL4264167 | 0.90 | TACR2 (0.65) | TACR2 | |
| SCHEMBL5802168 | 0.90 | TACR2 (0.65) | TACR2 | |
| SCHEMBL5011807 | 0.89 | TACR2 (0.66) | TACR2TACR1 | |
| SCHEMBL4256311 | 0.89 | TACR2 (0.49) | TACR2TACR1 | |
| SCHEMBL6002529 | 0.89 | TACR2 (0.68) | TACR2TACR1 | |
| SCHEMBL5013640 | 0.89 | TACR2 (0.68) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006062478-A1 | NOVEL TREATMENT OF GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2006-06-15 | — | — | WO | claimed |
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | claimed |
| WO-2006062478-A1 | NOVEL TREATMENT OF GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2006-06-15 | — | — | WO | disclosed |
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |