Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260274 | 0.91 | HDAC1 (0.49) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL5821196 | 0.85 | HDAC1 (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL8259679 | 0.85 | HDAC1 (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL8260770 | 0.83 | HDAC1 (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL8259001 | 0.83 | HDAC1 (0.67) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL5809231 | 0.83 | HDAC1 (0.67) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL8255855 | 0.83 | HDAC1 (0.61) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL5805384 | 0.83 | HDAC1 (0.61) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL5809262 | 0.82 | HDAC1 (0.59) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL8260764 | 0.82 | HDAC1 (0.59) | HDAC1HDAC8HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | claimed |