Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 18/20 | 0.53 |
| ▸ | TACR1 | P25103 | 3/20 | 0.53 |
| ▸ | TACR3 | P29371 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011918 | 1.00 | TACR2 (0.53) | TACR2TACR1TACR3 | |
| Acetic Acid SCHEMBL4261775 | 0.98 | TACR2 (0.52) | TACR2TACR1TACR3 | |
| SCHEMBL5801564 | 0.88 | TACR2 (0.67) | TACR2TACR1TACR3 | |
| SCHEMBL5015249 | 0.88 | TACR2 (0.67) | TACR2TACR1TACR3 | |
| Acetic Acid SCHEMBL6000659 | 0.86 | TACR2 (0.65) | TACR2TACR1TACR3 | |
| Acetic Acid SCHEMBL4262288 | 0.86 | TACR2 (0.65) | TACR2TACR1TACR3 | |
| SCHEMBL5820004 | 0.84 | TACR2 (0.52) | TACR2TACR1TACR3 | |
| SCHEMBL5015162 | 0.84 | TACR2 (0.52) | TACR2TACR1TACR3 | |
| Acetic Acid SCHEMBL4261883 | 0.83 | TACR2 (0.52) | TACR2TACR1TACR3 | |
| SCHEMBL5013680 | 0.82 | TACR2 (0.65) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | claimed |
| WO-2006062478-A1 | NOVEL TREATMENT OF GASTROINTESTINAL DISORDERS | ASTRAZENECA AB (SE) | 2006-06-15 | — | — | WO | disclosed |
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |