Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5805976 | 0.99 | TSHR (0.40) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL5811713 | 0.89 | HRH3 (0.36) | TSHRCHRM4L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5808672 | 0.88 | HRH3 (0.35) | TSHRCHRM4L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5806062 | 0.85 | TSHR (0.37) | TSHRALDH1A1KDM4EGAAGLA | |
| Hydrochloric Acid SCHEMBL5806094 | 0.85 | TSHR (0.31) | TSHR | |
| SCHEMBL5806843 | 0.84 | RPS6KA5 (0.42) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL5810664 | 0.83 | GRM2 (0.43) | ALDH1A1GAAHTTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL5810438 | 0.82 | GRM2 (0.42) | ALDH1A1GAAHTTSMN1; SMN2MEN1 | |
| SCHEMBL5806369 | 0.82 | KDM4E (0.42) | TSHRALDH1A1KDM4EGAAGLA | |
| Hydrochloric Acid SCHEMBL5807353 | 0.81 | KDM4E (0.42) | TSHRALDH1A1KDM4EGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |