Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 3/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.68 |
| ▸ | ESR1 | P03372 | 2/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.68 |
| ▸ | DRD3 | P35462 | 2/20 | 0.68 |
| ▸ | HTR6 | P50406 | 2/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13305510 | 0.93 | BCHE (0.77) | EBPSIGMAR1KMT2ACYP2D6MAPT | |
| SCHEMBL16561567 | 0.92 | KMT2A (0.59) | EBPSIGMAR1KMT2ACYP2D6MAPT | |
| SCHEMBL16561513 | 0.92 | GAA (0.64) | EBPSIGMAR1KMT2ACYP2D6MAPT | |
| SCHEMBL8770563 | 0.91 | BCHE (0.76) | EBPSIGMAR1KMT2ACYP2D6MAPT | |
| SCHEMBL1470323 | 0.90 | PPARA (0.62) | EBPSIGMAR1KMT2ACYP2D6MAPT | |
| SCHEMBL9360240 | 0.90 | BCHE (0.78) | BCHEACHEGAAPPARA | |
| SCHEMBL12748212 | 0.86 | BCHE (0.55) | EBPSIGMAR1KMT2ACYP2D6MAPT | |
| SCHEMBL250102 | 0.86 | EBP (0.69) | EBPSIGMAR1KMT2ACYP2D6MAPT | |
| SCHEMBL10882164 | 0.85 | GAA (0.59) | EBPSIGMAR1KMT2ACYP2D6MAPT | |
| SCHEMBL10885006 | 0.85 | EBP (0.55) | EBPSIGMAR1KMT2ACYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578025-B2 | Processes for the preparation of zuclomiphene intermediates | APOTEX INC. (CA) | 2023-02-14 | — | — | US | disclosed |
| US-20220119331-A1 | Processes for the Preparation of Zuclomiphene Intermediates | THE BANK OF NOVA SCOTIA (CA) | 2022-04-21 | — | — | US | disclosed |
| US-11046638-B2 | Processes for the preparation of zuclomiphene and intermediates thereof | APOTEX INC. (CA) | 2021-06-29 | — | — | US | disclosed |
| US-20210147337-A1 | Processes for the Preparation of Zuclomiphene and Intermediates Thereof | THE BANK OF NOVA SCOTIA (CA) | 2021-05-20 | — | — | US | disclosed |
| US-9012217-B2 | Benzimidazole compounds differentiate a mammalian stem cell into mesodermal or cardiomyocyte cells | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2015-04-21 | — | — | US | disclosed |
| US-9012217-B2 | Benzimidazole compounds differentiate a mammalian stem cell into mesodermal or cardiomyocyte cells | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2015-04-21 | — | — | US | disclosed |
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2006108204-A1 | PHOTOPOLYMERISABLE MIXTURES COMPRISING PHOTOINITIATORS BASED ON BENZOPHENONE AND PHENYLGLYCINE | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2006-10-19 | — | — | WO | disclosed |
| US-4094908-A | Alpha-substituted benzhydrol derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-06-13 | — | — | US | disclosed |
| US-4082813-A | 3-Ioda-α-ethynyl benzhydrol | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-04-04 | — | — | US | disclosed |
| US-4066709-A | α-Ethyny benzhydrols | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-01-03 | — | — | US | disclosed |
| US-4039589-A | LIVER MICROSOMAL ENZYMES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1977-08-02 | — | — | US | disclosed |
| US-3965179-A | BLOCKING, VIRICIDE, FUNGICIDE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578025-B2 | Processes for the preparation of zuclomiphene intermediates | CYP4F2, CYP4F12, CYP1A2 | EBP 409/4885SIGMAR1 4558/4885KMT2A 275/4885 |
| US-11046638-B2 | Processes for the preparation of zuclomiphene and intermediates thereof | CYP3A43, UGT1A3, ZDHHC7 | EBP 576/4885SIGMAR1 4764/4885KMT2A 897/4885 |
| US-20210147337-A1 | Processes for the Preparation of Zuclomiphene and Intermediates Thereof | CYP3A43, UGT1A3, ZDHHC7 | EBP 576/4885SIGMAR1 4764/4885KMT2A 897/4885 |
| US-20220119331-A1 | Processes for the Preparation of Zuclomiphene Intermediates | CYP4F2, CYP4F12, CYP1A2 | EBP 409/4885SIGMAR1 4558/4885KMT2A 275/4885 |
| US-20100159596-A1 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION | RCOR3, BRD3, BRPF3 | EBP 323/4885SIGMAR1 1897/4885KMT2A 1143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.