SCHEMBL5810194

SCHEMBL5810194

Cc1nn(C)c2nc(C(NCC3CC3)C3CCC3)c(CN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c3nnn(C)n3)cc12

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5623737 0.84 CETP (0.36) CETP
SCHEMBL5623851 0.84 CETP (0.37) CETP
SCHEMBL5623985 0.84 CETP (0.37) CETP
SCHEMBL27901999 0.83 CETP (0.37) CETP
SCHEMBL5624482 0.83 CETP (0.35) CETP
SCHEMBL5624398 0.83 CETP (0.35) CETP
SCHEMBL19189389 0.82 CETP (0.38) CETP
SCHEMBL5623853 0.82 CETP (0.38) CETP
SCHEMBL27901983 0.82 CETP (0.38) CETP
SCHEMBL5624903 0.81 CETP (0.35) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1848430-A2 NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS Reddy US Therapeutics, Inc. (US) 2007-10-31 EP claimed
WO-2006073973-A2 NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS REDDY US THERAPEUTICS, INC. (US) 2006-07-13 WO claimed