⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2041622 | 0.64 | — | — | |
| SCHEMBL9045723 | 0.60 | — | — | |
| SCHEMBL2040738 | 0.60 | — | — | |
| SCHEMBL25959129 | 0.59 | — | — | |
| SCHEMBL2042577 | 0.59 | — | — | |
| SCHEMBL5730522 | 0.58 | — | — | |
| SCHEMBL4061595 | 0.54 | — | — | |
| SCHEMBL385496 | 0.53 | — | — | |
| SCHEMBL1993310 | 0.52 | — | — | |
| SCHEMBL1997882 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069390-A2 | OPSIN STABILIZING COMPOUNDS AND METHODS OF USE | University of Florida Research Foundation, Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| WO-2008013983-A2 | OPSIN STABILIZING COMPOUNDS AND METHODS OF USE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| EP-3373936-A1 | 4-(4-CYANO-2-THIOARYL)DIHYDROPYRIMIDINONES FOR TREATING CHRONIC WOUNDS | Bayer Pharma Aktiengesellschaft (DE) | 2018-09-19 | — | — | EP | disclosed |
| WO-2017081044-A1 | 4-(4-CYANO-2-THIOARYL)DIHYDROPYRIMIDINONES FOR TREATING CHRONIC WOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-05-18 | — | — | WO | disclosed |
| EP-2417112-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTITUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115548-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTITUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | WO | disclosed |