Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 19/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266239 | 0.88 | CHRM2 (0.56) | CHRM2CHRM3ADRB2 | |
| SCHEMBL266141 | 0.84 | CHRM2 (0.69) | CHRM2CHRM3 | |
| SCHEMBL381835 | 0.81 | CHRM2 (0.66) | CHRM2CHRM3ADRB2 | |
| SCHEMBL265681 | 0.81 | CHRM2 (0.62) | CHRM2CHRM3 | |
| SCHEMBL267098 | 0.81 | CHRM2 (0.62) | CHRM2CHRM3 | |
| SCHEMBL266338 | 0.80 | CHRM2 (0.65) | CHRM2CHRM3 | |
| SCHEMBL5276987 | 0.80 | CHRM2 (0.56) | CHRM2CHRM3ADRB2 | |
| SCHEMBL265736 | 0.80 | CHRM2 (0.60) | CHRM2CHRM3 | |
| SCHEMBL265206 | 0.79 | CHRM2 (0.64) | CHRM2CHRM3 | |
| SCHEMBL264491 | 0.79 | CHRM2 (0.59) | CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006099091-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-09-21 | — | — | WO | disclosed |