Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811083 | 0.88 | AKR1C3 (0.48) | PPARGPPARAAKR1C3PTGS2AKR1C2 | |
| SCHEMBL6424050 | 0.87 | PPARG (0.46) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL6426691 | 0.87 | PPARG (0.46) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL6427280 | 0.82 | PPARG (0.43) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL6423711 | 0.82 | PPARG (0.43) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL6423391 | 0.82 | PPARG (0.46) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL6423236 | 0.82 | PPARG (0.46) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL6423929 | 0.81 | PPARG (0.42) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL5560502 | 0.81 | HRH3 (0.41) | PPARGPPARAAKR1C3PTGS2AKR1C2 | |
| SCHEMBL5560498 | 0.81 | HRH3 (0.41) | PPARGPPARAAKR1C3PTGS2AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |