Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 4/20 | 0.47 |
| ▸ | ALPL | P05186 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811555 | 1.00 | HDAC6 (0.63) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5799712 | 0.90 | HDAC3 (0.50) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5796586 | 0.90 | HDAC3 (0.50) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5799709 | 0.90 | HDAC3 (0.50) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5797716 | 0.87 | HDAC6 (0.66) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5797720 | 0.87 | HDAC6 (0.66) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5808188 | 0.85 | HDAC6 (0.74) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5796842 | 0.84 | HDAC6 (0.62) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5797816 | 0.82 | HDAC6 (0.69) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5796258 | 0.81 | HDAC1 (0.60) | HDAC6HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |