Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5808644 | 0.99 | NPC1 (0.46) | NPC1MAPTLMNANPSR1RXFP1 | |
| SCHEMBL5806150 | 0.89 | MAPT (0.49) | NPC1MAPTLMNANPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL5811160 | 0.89 | MAPT (0.43) | NPC1MAPTLMNANPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL5810209 | 0.88 | MAPT (0.48) | NPC1MAPTLMNANPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL5806692 | 0.86 | MAPT (0.46) | NPC1MAPTLMNANPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL5808654 | 0.86 | MAPT (0.46) | NPC1MAPTLMNANPSR1RXFP1 | |
| SCHEMBL5806149 | 0.86 | NPC1 (0.46) | NPC1MAPTLMNANPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL5809237 | 0.85 | NPC1 (0.45) | NPC1MAPTLMNANPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL5810820 | 0.85 | NPC1 (0.45) | NPC1MAPTLMNANPSR1RXFP1 | |
| Hydrochloric Acid SCHEMBL5806436 | 0.84 | MAPT (0.44) | NPC1MAPTLMNANPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |