Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 17/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654761 | 0.91 | HPGD (0.53) | HPGDFGFR1ALDH1A1NPC1GLA | |
| SCHEMBL7242552 | 0.90 | HPGD (0.56) | HPGDFGFR1ALDH1A1NPC1GLA | |
| SCHEMBL2651498 | 0.89 | HPGD (0.56) | HPGDFGFR1ALDH1A1NPC1GLA | |
| SCHEMBL2649744 | 0.88 | HPGD (0.60) | HPGDFGFR1ALDH1A1NPC1GLA | |
| SCHEMBL2651819 | 0.87 | HPGD (0.55) | HPGDFGFR1ALDH1A1NPC1GLA | |
| SCHEMBL2647587 | 0.83 | FGFR1 (0.68) | HPGDFGFR1ALDH1A1NPC1GLA | |
| SCHEMBL6752588 | 0.82 | HPGD (0.54) | HPGDFGFR1ALDH1A1NPC1GLA | |
| SCHEMBL7241895 | 0.82 | HPGD (0.56) | HPGDFGFR1ALDH1A1NPC1GLA | |
| SCHEMBL2944419 | 0.81 | HPGD (0.58) | HPGDFGFR1ALDH1A1NPC1GLA | |
| SCHEMBL2653578 | 0.81 | FGFR1 (0.48) | HPGDFGFR1ALDH1A1NPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2006-01-18 | — | — | EP | disclosed |