Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17873924 | 0.88 | SMN1; SMN2 (0.76) | SMN1; SMN2ALDH1A1HTR1AHTR2ADRD3 | |
| SCHEMBL17554031 | 0.88 | POLB (0.79) | SMN1; SMN2ALDH1A1KDM4EHTR1AHTR2A | |
| SCHEMBL29672523 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL2772319 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1HTR1AHTR2ADRD3 | |
| SCHEMBL1382764 | 0.84 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL17554140 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1KDM4EHTR1AHTR2A | |
| SCHEMBL17554169 | 0.83 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1KDM4EHTR1AHTR2A | |
| SCHEMBL17554081 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL17554021 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HTR1AHTR2ADRD3 | |
| SCHEMBL30560579 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1KDM4ETSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006068410-A1 | NOVEL 3-(2-AMINO-6-PYRIDINYL)-4-HYDROXYPHENYL AMINE DERIVATIVES | LG LIFE SCIENCES, LTD. (KR) | 2006-06-29 | — | — | WO | claimed |