Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | VEGFA | P15692 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819280 | 0.88 | KMT2A (0.64) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL28578470 | 0.85 | KMT2A (0.60) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL28578472 | 0.85 | KMT2A (0.60) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL5536182 | 0.81 | VEGFA (0.68) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL2932582 | 0.81 | VEGFA (0.62) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL1256025 | 0.81 | KMT2A (0.92) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL28575980 | 0.79 | KMT2A (0.54) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL32667348 | 0.78 | VEGFA (0.64) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL31466182 | 0.78 | KMT2A (0.64) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL5099893 | 0.78 | CNR1 (0.54) | KMT2AMEN1HTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006072350-A1 | CYANOGUANIDINE-SUBSTITUTED PYRAZOLINES | BAYER HEALTHCARE AG (DE) | 2006-07-13 | — | — | WO | disclosed |
| WO-2006072353-A1 | AZETIDINE-SUBSTITUTED PYRAZOLINES AS PAR-1 ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2006-07-13 | — | — | WO | disclosed |