Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815262 | 1.00 | POLB (0.41) | POLBPPARGPPARAHSD17B10KDM4E | |
| SCHEMBL5810168 | 0.95 | POLB (0.41) | POLBPPARGPPARAHSD17B10KDM4E | |
| SCHEMBL5810162 | 0.95 | POLB (0.41) | POLBPPARGPPARAHSD17B10KDM4E | |
| SCHEMBL5814061 | 0.93 | PPARG (0.46) | POLBPPARGPPARAKDM4E | |
| SCHEMBL5814066 | 0.93 | PPARG (0.46) | POLBPPARGPPARAKDM4E | |
| SCHEMBL5812488 | 0.93 | PPARG (0.40) | PPARGPPARAHSD17B10KDM4EMAPT | |
| SCHEMBL5813524 | 0.91 | POLB (0.46) | POLBPPARGPPARAHSD17B10KDM4E | |
| SCHEMBL5813522 | 0.91 | POLB (0.46) | POLBPPARGPPARAHSD17B10KDM4E | |
| SCHEMBL5809650 | 0.89 | PPARG (0.41) | PPARGPPARAHSD17B10KDM4EMAPT | |
| SCHEMBL5815267 | 0.88 | PPARG (0.48) | POLBPPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |