Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815862 | 0.96 | KCNH2 (0.51) | KCNH2ACHE | |
| SCHEMBL5818160 | 0.95 | KCNH2 (0.51) | KCNH2ACHE | |
| SCHEMBL5818526 | 0.87 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL5819150 | 0.84 | KCNH2 (0.72) | KCNH2ACHE | |
| SCHEMBL5824185 | 0.84 | MAPK13 (0.51) | KCNH2ACHE | |
| Hydrochloric Acid SCHEMBL17629709 | 0.83 | KCNH2 (0.71) | KCNH2ACHE | |
| Hydrochloric Acid SCHEMBL30286806 | 0.83 | KCNH2 (0.71) | KCNH2ACHE | |
| SCHEMBL5813737 | 0.83 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL5817342 | 0.83 | KCNH2 (0.59) | KCNH2ACHE | |
| SCHEMBL5818808 | 0.83 | KCNH2 (0.50) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |