SCHEMBL5816465

SCHEMBL5816465

CCOC(=O)C(OCC)c1ccc(OCCN(C)c2nc3ccccc3o2)cc1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.67
PPARA Q07869 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5805154 0.91 PPARG (0.74) PPARGPPARA
SCHEMBL7815200 0.85 PPARG (0.85) PPARGPPARA
SCHEMBL5807104 0.85 PPARG (0.68) PPARGPPARA
SCHEMBL9393956 0.84 PPARG (0.74) PPARGPPARA
SCHEMBL8056866 0.84 PPARG (0.73) PPARGPPARA
SCHEMBL5807156 0.83 PPARG (0.73) PPARGPPARA
SCHEMBL9086955 0.82 PPARG (0.71) PPARGPPARA
SCHEMBL7815895 0.81 PPARG (0.81) PPARGPPARA
SCHEMBL13649244 0.81 PPARG (0.78) PPARGPPARA
SCHEMBL7824139 0.81 PPARG (0.83) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006082495-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS RANBAXY LABORATORIES LIMITED (IN) 2006-08-10 WO claimed
WO-2006082495-A1 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS RANBAXY LABORATORIES LIMITED (IN) 2006-08-10 WO disclosed