⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620493 | 0.79 | — | — | |
| SCHEMBL338632 | 0.79 | — | — | |
| SCHEMBL30661614 | 0.79 | — | — | |
| SCHEMBL9682588 | 0.75 | — | — | |
| SCHEMBL10768918 | 0.75 | — | — | |
| SCHEMBL9682583 | 0.75 | — | — | |
| SCHEMBL20844096 | 0.75 | — | — | |
| SCHEMBL29372810 | 0.72 | — | — | |
| SCHEMBL155314 | 0.72 | — | — | |
| SCHEMBL10952404 | 0.72 | RPS6KA5 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10792282-B2 | Protein kinase C inhibitors and uses thereof | RIGEL PHARMACEUTICALS, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| EP-3296309-B1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | UNIV GENT (BE) | 2019-08-07 | — | — | EP | disclosed |
| US-10005777-B2 | Protein kinase C inhibitors and uses thereof | RIGEL PHARMACEUTICALS, INC. (US) | 2018-06-26 | — | — | US | disclosed |
| EP-2970275-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2018-05-09 | — | — | EP | disclosed |
| EP-3296309-A1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | Universiteit Gent (BE) | 2018-03-21 | — | — | EP | disclosed |
| US-20180030050-A1 | Protein Kinase C Inhibitors and Uses Thereof | MIDCAP FINANCIAL TRUST | 2018-02-01 | — | — | US | disclosed |
| US-20170360786-A1 | Protein Kinase C Inhibitors and Uses Thereof | RIGEL PHARMACEUTICALS, INC. | 2017-12-21 | — | — | US | disclosed |
| EP-2833889-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-2877480-B1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | UNIV GENT (BE) | 2017-09-06 | — | — | EP | disclosed |
| US-9682976-B2 | Protein kinase C inhibitors and uses thereof | RIGEL PHARMACEUTICALS, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| WO-2007087276-A1 | AURORA KINASE MODULATORS AND METHOD OF USE | AMGEN INC. (US) | 2007-08-02 | — | — | WO | disclosed |
| EP-1185505-B1 | METHOD OF PRODUCING METHOXYIMINO ACETIC AMIDE | BAYER CROPSCIENCE AG (DE) | 2004-11-03 | — | — | EP | disclosed |
| US-6660872-B1 | In high yields | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-09 | — | — | US | disclosed |
| EP-1185505-A1 | METHOD OF PRODUCING METHOXYIMINO ACETIC AMIDE | Bayer Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000071504-A1 | METHOD OF PRODUCING METHOXYIMINO ACETIC AMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-30 | — | — | WO | disclosed |
| US-5882356-A | Fibre treatment | COURTAULDS FIBRES (HOLDINGS) LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |
| EP-0665904-B1 | FIBRE TREATMENT | COURTAULDS FIBRES HOLDINGS LTD (GB) | 1998-11-18 | — | — | EP | disclosed |
| EP-0665904-A1 | FIBRE TREATMENT | COURTAULDS FIBRES (HOLDINGS) LIMITED (GB) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994009191-A1 | FIBRE TREATMENT | COURTAULDS FIBRES (HOLDINGS) LIMITED (GB) | 1994-04-28 | — | — | WO | disclosed |
| EP-0016931-A2 | Reactive azo dyestuffs, their use in dyeing and printing materials containing amide or hydroxyl groups | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |