Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.52 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.52 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.52 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.52 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819036 | 0.87 | CDK2 (0.49) | CSNK1DPRKD3MAP4K4CDK2MAPK1 | |
| SCHEMBL5823170 | 0.84 | CSNK1D (0.46) | CSNK1DPRKD3MAP4K4CDK2MAPK1 | |
| SCHEMBL5818548 | 0.83 | PRKD3 (0.57) | PRKD3MAP4K4MAPK1MAPK8MAPK9 | |
| SCHEMBL5818495 | 0.80 | EGFR (0.51) | KCNH2EGFR | |
| SCHEMBL5814596 | 0.79 | KCNH2 (0.49) | KCNH2EGFR | |
| SCHEMBL5816278 | 0.77 | EGFR (0.54) | KCNH2EGFR | |
| SCHEMBL5817196 | 0.77 | EGFR (0.52) | KCNH2EGFR | |
| SCHEMBL5812894 | 0.76 | EGFR (0.50) | KCNH2EGFR | |
| SCHEMBL5817608 | 0.76 | CDK2 (0.43) | CSNK1DPRKD3MAP4K4CDK2MAPK1 | |
| SCHEMBL5816188 | 0.76 | CDK2 (0.44) | CSNK1DPRKD3MAP4K4CDK2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |