Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.71 |
| ▸ | MAPK13 | O15264 | 15/20 | 0.71 |
| ▸ | MAPK12 | P53778 | 15/20 | 0.71 |
| ▸ | MAPK11 | Q15759 | 15/20 | 0.71 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.57 |
| ▸ | RAF1 | P04049 | 3/20 | 0.56 |
| ▸ | IDH1 | O75874 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817836 | 0.91 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5815416 | 0.90 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5818817 | 0.89 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL6215614 | 0.86 | MAPK13 (0.51) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL6215613 | 0.86 | MAPK13 (0.51) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5818729 | 0.86 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5819478 | 0.84 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5818802 | 0.84 | MAPK13 (0.50) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5816128 | 0.83 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5819635 | 0.83 | MAPK13 (0.62) | MAPK14MAPK13MAPK12MAPK11MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |