Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897259 | 0.90 | HDAC1 (0.69) | HDAC1KCNH2HDAC2 | |
| SCHEMBL3622271 | 0.89 | HDAC1 (0.70) | HDAC1KCNH2HDAC2 | |
| SCHEMBL2077612 | 0.87 | HDAC1 (0.71) | HDAC1KCNH2 | |
| SCHEMBL5819219 | 0.86 | HDAC1 (0.54) | HDAC1KCNH2HDAC2 | |
| SCHEMBL4887537 | 0.82 | HDAC1 (0.67) | HDAC1KCNH2HDAC2HDAC3 | |
| SCHEMBL30444370 | 0.82 | HDAC1 (0.68) | HDAC1KCNH2HDAC2HDAC3 | |
| SCHEMBL3618240 | 0.82 | HDAC1 (0.68) | HDAC1KCNH2HDAC2HDAC3 | |
| SCHEMBL4892787 | 0.81 | HDAC1 (0.65) | HDAC1KCNH2HDAC2HDAC3 | |
| SCHEMBL2759480 | 0.80 | HDAC1 (0.74) | HDAC1HDAC2HDAC3 | |
| SCHEMBL12842027 | 0.80 | HDAC1 (0.54) | HDAC1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006077387-A2 | NOVEL BENZAMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2006-07-27 | — | — | WO | disclosed |