SCHEMBL5819253

SCHEMBL5819253

CSc1nccc(-c2sc(C3CCNCC3)nc2-c2ccc(F)cc2)n1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 7/20 0.64
ACHE P22303 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5815508 0.87 KCNH2 (0.59) KCNH2
SCHEMBL29039437 0.86 KCNH2 (0.68) KCNH2ACHE
SCHEMBL30408745 0.86 KCNH2 (0.68) KCNH2ACHE
SCHEMBL5818012 0.84 KCNH2 (0.66) KCNH2ACHE
SCHEMBL5819409 0.82 KCNH2 (0.62) KCNH2ACHE
SCHEMBL5819408 0.82 KCNH2 (0.62) KCNH2ACHE
SCHEMBL5819150 0.81 KCNH2 (0.72) KCNH2ACHE
SCHEMBL5818010 0.81 KCNH2 (0.63) KCNH2ACHE
Hydrochloric Acid SCHEMBL17629709 0.80 KCNH2 (0.71) KCNH2ACHE
Hydrochloric Acid SCHEMBL30286806 0.80 KCNH2 (0.71) KCNH2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006137658-A1 NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DONGBU HITEK CO., LTD. (KR) 2006-12-28 WO claimed
WO-2006137658-A1 NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DONGBU HITEK CO., LTD. (KR) 2006-12-28 WO disclosed