Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | EGFR | P00533 | 7/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815854 | 0.90 | EGFR (0.62) | KCNH2EGFR | |
| SCHEMBL5819551 | 0.89 | KCNH2 (0.58) | KCNH2EGFR | |
| SCHEMBL5819446 | 0.89 | EGFR (0.51) | KCNH2EGFRMAPK14 | |
| SCHEMBL5816278 | 0.88 | EGFR (0.54) | KCNH2EGFR | |
| SCHEMBL5818153 | 0.87 | EGFR (0.57) | KCNH2EGFRMAPK14 | |
| SCHEMBL6220155 | 0.87 | EGFR (0.57) | KCNH2EGFRMAPK14 | |
| SCHEMBL6220153 | 0.87 | EGFR (0.57) | KCNH2EGFRMAPK14 | |
| SCHEMBL5819627 | 0.87 | EGFR (0.54) | KCNH2EGFRMAPK14 | |
| SCHEMBL5819187 | 0.86 | EGFR (0.53) | KCNH2EGFR | |
| SCHEMBL5819594 | 0.85 | EGFR (0.52) | KCNH2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |