Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816099 | 1.00 | TP53 (0.60) | TP53TSHRPLA2G4BLTA4HRARB | |
| SCHEMBL5819931 | 1.00 | TP53 (0.60) | TP53TSHRPLA2G4BLTA4HRARB | |
| SCHEMBL5814527 | 0.94 | TP53 (0.68) | TP53TSHRPLA2G4BLTA4HRARB | |
| SCHEMBL4800576 | 0.94 | TP53 (0.63) | TP53TSHRPLA2G4BLTA4HRARB | |
| SCHEMBL5820211 | 0.94 | TP53 (0.68) | TP53TSHRPLA2G4BLTA4HRARB | |
| SCHEMBL4798961 | 0.94 | TP53 (0.68) | TP53TSHRPLA2G4BLTA4HRARB | |
| SCHEMBL4796415 | 0.94 | TP53 (0.63) | TP53TSHRPLA2G4BLTA4HRARB | |
| SCHEMBL382628 | 0.94 | TP53 (0.68) | TP53TSHRPLA2G4BLTA4HRARB | |
| SCHEMBL382171 | 0.94 | TP53 (0.68) | TP53TSHRPLA2G4BLTA4HRARB | |
| SCHEMBL4799801 | 0.94 | TP53 (0.63) | TP53TSHRPLA2G4BLTA4HRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006132588-A1 | METHOD FOR THE PURIFICATION OF SYNTHETIC OLIGONUCLEOTIDES CONTAINING ONE OR SEVERAL LABELS | QUIATECH AB (SE) | 2006-12-14 | — | — | WO | claimed |
| WO-2006132588-A1 | METHOD FOR THE PURIFICATION OF SYNTHETIC OLIGONUCLEOTIDES CONTAINING ONE OR SEVERAL LABELS | QUIATECH AB (SE) | 2006-12-14 | — | — | WO | disclosed |