Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.59 |
| ▸ | HRH1 | P35367 | 6/20 | 0.59 |
| ▸ | HTR2B | P41595 | 6/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6831616 | 0.94 | MCHR1 (0.69) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| Trifluoroacetic Acid SCHEMBL6456478 | 0.94 | MCHR1 (0.69) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| Trifluoroacetic Acid SCHEMBL6455569 | 0.89 | MCHR1 (0.67) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| Trifluoroacetic Acid SCHEMBL6833473 | 0.89 | MCHR1 (0.67) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL4258540 | 0.88 | MCHR1 (0.71) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL4258534 | 0.88 | MCHR1 (0.71) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6463341 | 0.87 | MCHR1 (1.00) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6463334 | 0.87 | MCHR1 (1.00) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| Trifluoroacetic Acid SCHEMBL6459409 | 0.86 | MCHR1 (0.64) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| Trifluoroacetic Acid SCHEMBL6456496 | 0.86 | MCHR1 (0.65) | MCHR1ADRA2AHRH1HTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006091737-A1 | MODULATORS OF GSK-3 ACTIVITY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | claimed |