Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 20/20 | 0.78 |
| ▸ | MAPK9 | P45984 | 17/20 | 0.78 |
| ▸ | RPS27 | P42677 | 1/20 | 0.77 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.75 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.60 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.60 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.60 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.60 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145006 | 0.90 | MAPK8 (0.80) | MAPK8MAPK9RPS27MAPK10PRKD2 | |
| SCHEMBL5818749 | 0.89 | MAPK8 (0.84) | MAPK8MAPK9RPS27MAPK10PRKD2 | |
| SCHEMBL1145342 | 0.88 | MAPK8 (1.00) | MAPK8MAPK9RPS27MAPK10PRKD2 | |
| SCHEMBL1145640 | 0.87 | MAPK8 (1.00) | MAPK8MAPK9RPS27MAPK10PRKD2 | |
| SCHEMBL1145045 | 0.87 | MAPK8 (0.81) | MAPK8MAPK9RPS27MAPK10PRKD2 | |
| SCHEMBL1145568 | 0.87 | MAPK8 (0.81) | MAPK8MAPK9RPS27MAPK10PRKD2 | |
| SCHEMBL1145468 | 0.87 | MAPK8 (1.00) | MAPK8MAPK9RPS27MAPK10PRKD2 | |
| SCHEMBL1145077 | 0.86 | MAPK8 (1.00) | MAPK8MAPK9RPS27MAPK10PRKD2 | |
| SCHEMBL1145565 | 0.84 | MAPK8 (0.77) | MAPK8MAPK9RPS27MAPK10PRKD2 | |
| SCHEMBL1145373 | 0.84 | MAPK8 (0.81) | MAPK8MAPK9RPS27MAPK10PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006083673-A2 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES | ABBOTT LABORATORIES (US) | 2006-08-10 | — | — | WO | disclosed |