SCHEMBL5820356

SCHEMBL5820356

CC(=C(F)C(=O)NCc1ccc(NS(C)(=O)=O)c(F)c1)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 4/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5820350 1.00 TRPV1 (0.66) TRPV1
SCHEMBL5802221 0.89 TRPV1 (0.71) TRPV1
SCHEMBL5802227 0.89 TRPV1 (0.71) TRPV1
SCHEMBL4891141 0.86 TRPV1 (0.76) TRPV1
SCHEMBL5803317 0.84 EPHX2 (0.49) TRPV1
SCHEMBL5803313 0.84 EPHX2 (0.49) TRPV1
SCHEMBL2003664 0.83 TRPV1 (0.81) TRPV1
SCHEMBL2004367 0.82 TRPV1 (0.66) TRPV1
SCHEMBL2004249 0.82 TRPV1 (0.66) TRPV1
SCHEMBL12567983 0.82 TRPV1 (0.66) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006098554-A1 NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AMOREPACIFIC CORPORATION (KR) 2006-09-21 WO disclosed