Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819178 | 0.87 | EGFR (0.46) | EGFRKCNH2 | |
| SCHEMBL5819435 | 0.87 | EGFR (0.48) | EGFRKCNH2ACHE | |
| SCHEMBL5820361 | 0.86 | EGFR (0.42) | EGFRKCNH2 | |
| SCHEMBL5819403 | 0.85 | EGFR (0.43) | EGFRKCNH2 | |
| SCHEMBL5812894 | 0.85 | EGFR (0.50) | EGFRKCNH2ACHE | |
| Cyclohexane SCHEMBL5820492 | 0.85 | GRIA1 (0.47) | EGFRKCNH2 | |
| SCHEMBL5812942 | 0.81 | EGFR (0.57) | EGFRKCNH2 | |
| SCHEMBL5819552 | 0.77 | MAPK14 (0.64) | EGFRKCNH2 | |
| SCHEMBL5818093 | 0.77 | EGFR (0.51) | EGFRKCNH2ACHE | |
| SCHEMBL5819594 | 0.76 | EGFR (0.52) | EGFRKCNH2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |