Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 8/20 | 0.64 |
| ▸ | CCNB2 | O95067 | 7/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.62 |
| ▸ | GSK3B | P49841 | 7/20 | 0.62 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 0.62 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819849 | 0.92 | CDK1 (0.66) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5805246 | 0.85 | CDK1 (0.73) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5802549 | 0.84 | CDK1 (0.71) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5802581 | 0.82 | CDK1 (0.69) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5801919 | 0.82 | CDK1 (0.69) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5801923 | 0.80 | CDK1 (0.79) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5819148 | 0.79 | CDK1 (0.66) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5819011 | 0.79 | CDK1 (0.55) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5688713 | 0.79 | CDK1 (1.00) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL5688439 | 0.77 | GSK3B (1.00) | CDK1CCNB2CCNB1GSK3BCCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006089874-A1 | BENZO[2,3]AZEPINO[4,5-B]INDOL-6-ONES | GPC BIOTECH AG (DE) | 2006-08-31 | — | — | WO | disclosed |