Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1485557 | 0.98 | TSHR (0.38) | TSHRTHRBSIRT2DNM1MEN1 | |
| SCHEMBL561544 | 0.98 | CETP (0.33) | TSHRTHRBSIRT2DNM1MEN1 | |
| SCHEMBL9212395 | 0.98 | TSHR (0.38) | TSHRTHRBSIRT2DNM1MEN1 | |
| SCHEMBL9211485 | 0.98 | TSHR (0.38) | TSHRTHRBSIRT2DNM1MEN1 | |
| SCHEMBL9210550 | 0.98 | TSHR (0.38) | TSHRTHRBSIRT2DNM1MEN1 | |
| SCHEMBL9202179 | 0.98 | TSHR (0.38) | TSHRTHRBSIRT2DNM1MEN1 | |
| SCHEMBL9211964 | 0.98 | TSHR (0.38) | TSHRTHRBSIRT2DNM1MEN1 | |
| SCHEMBL9214248 | 0.98 | TSHR (0.38) | TSHRTHRBSIRT2DNM1MEN1 | |
| SCHEMBL6063488 | 0.95 | TSHR (0.36) | TSHRTHRBSIRT2DNM1MEN1 | |
| SCHEMBL6061746 | 0.95 | TSHR (0.36) | TSHRTHRBSIRT2DNM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102308-A2 | BETA-LACTAMYL VASOPRESSIN V1B ANTAGONISTS | AZEVAN PHARMACEUTICALS, INC. (US) | 2006-09-28 | — | — | WO | claimed |
| US-10677953-B2 | Magneto-optical detecting apparatus and methods | LOCKHEED MARTIN CORPORATION (US) | 2020-06-09 | — | — | US | disclosed |
| EP-2316846-B1 | Spatially-defined macrocyclic compounds useful for drug discovery | OCERA THERAPEUTICS INC (US) | 2019-10-02 | — | — | EP | disclosed |
| US-20170343695-A1 | Magneto-Optical Detecting Apparatus and Methods | LOCKHEED MARTIN CORPORATION (US) | 2017-11-30 | — | — | US | disclosed |
| WO-2006102308-A2 | BETA-LACTAMYL VASOPRESSIN V1B ANTAGONISTS | AZEVAN PHARMACEUTICALS, INC. (US) | 2006-09-28 | — | — | WO | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |