Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819264 | 0.88 | KLKB1 (0.57) | KLKB1CARM1 | |
| SCHEMBL5821995 | 0.88 | KLKB1 (0.57) | KLKB1CARM1 | |
| SCHEMBL5475957 | 0.85 | CARM1 (0.48) | ALDH1A1KLKB1CARM1MAPT | |
| SCHEMBL5475948 | 0.85 | CARM1 (0.48) | ALDH1A1KLKB1CARM1MAPT | |
| SCHEMBL18622976 | 0.82 | MAPT (0.48) | ALDH1A1KLKB1CARM1MAPTGRN | |
| SCHEMBL5822099 | 0.81 | CARM1 (0.49) | KLKB1CARM1 | |
| SCHEMBL5819442 | 0.79 | CARM1 (0.56) | KLKB1CARM1 | |
| SCHEMBL22897252 | 0.76 | MAPT (0.50) | ALDH1A1KLKB1CARM1MAPTKMT2A | |
| SCHEMBL20027768 | 0.75 | MAPT (0.52) | ALDH1A1KLKB1CARM1MAPTKMT2A | |
| SCHEMBL27922621 | 0.75 | ATM (0.60) | ALDH1A1MAPTKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006069155-A2 | INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |