Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1690261 | 0.81 | PTGDR2 (0.52) | PTGDR2 | |
| SCHEMBL1753610 | 0.79 | PTGDR2 (0.49) | PTGDR2 | |
| SCHEMBL1690393 | 0.79 | PTGDR2 (0.49) | PTGDR2 | |
| SCHEMBL1753792 | 0.78 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL2112021 | 0.77 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL1753608 | 0.77 | PTGDR2 (0.47) | PTGDR2 | |
| SCHEMBL1753556 | 0.77 | PTGDR2 (0.58) | PTGDR2 | |
| SCHEMBL1690280 | 0.77 | PTGDR2 (0.55) | PTGDR2PPARD | |
| SCHEMBL2114849 | 0.77 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL5764339 | 0.75 | PTGDR2 (0.51) | PTGDR2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611091-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2006-01-04 | — | — | EP | claimed |
| WO-2004089885-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | claimed |