⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013288 | 0.63 | — | — | |
| SCHEMBL453907 | 0.62 | — | — | |
| SCHEMBL429415 | 0.56 | — | — | |
| SCHEMBL7476084 | 0.55 | — | — | |
| SCHEMBL7478715 | 0.55 | — | — | |
| SCHEMBL46423 | 0.54 | — | — | |
| SCHEMBL14872305 | 0.52 | — | — | |
| SCHEMBL2054430 | 0.51 | — | — | |
| SCHEMBL3459509 | 0.51 | IDO1 (0.51) | — | |
| SCHEMBL7384422 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | claimed |
| US-6093738-A | IMIDAZO(1,2-D)-THIADIAZOLE COMPOUNDS; PEPTIC ULCER TREATMENT | KARIMIAN KHASHAYAR (CA) | 2000-07-25 | — | — | US | claimed |
| WO-2006128129-A2 | METHOD FOR TREATING CANCER | SYNTA PHARMACEUTICALS CORP. (US) | 2006-11-30 | — | — | WO | disclosed |
| EP-0883622-B1 | PROTON PUMP INHIBITOR | APOTEX INC (CA) | 2002-05-15 | — | — | EP | disclosed |
| US-6114537-A | 1,2,4-THIADIAZOLE COMPOUND IS USEFUL FOR TRAPPING THIOL COMPOUNDS AND SELECTIVELY CHANGING THIOLS TO DISULFIDE COMPOUNDS | APOTEX INC. (CA) | 2000-09-05 | — | — | US | disclosed |
| US-6093738-A | IMIDAZO(1,2-D)-THIADIAZOLE COMPOUNDS; PEPTIC ULCER TREATMENT | KARIMIAN KHASHAYAR (CA) | 2000-07-25 | — | — | US | disclosed |
| US-6060472-A | Thiadiazole compounds useful as inhibitors of H+ /K+ atpase | APOTEX INC. (CA) | 2000-05-09 | — | — | US | disclosed |
| WO-1999051584-A1 | THIADIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF H+/K+ ATPASE | APOTEX INC. (CA) | 1999-10-14 | — | — | WO | disclosed |