Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583842 | 0.89 | PDE4B (0.58) | PDE4BADORA1 | |
| SCHEMBL583106 | 0.89 | PDE4B (0.58) | PDE4BADORA1 | |
| SCHEMBL583482 | 0.87 | PDE4B (0.65) | PDE4BADORA1 | |
| SCHEMBL1942142 | 0.87 | PDE4B (0.54) | PDE4BADORA1 | |
| SCHEMBL582862 | 0.86 | PDE4B (0.73) | PDE4BADORA1 | |
| SCHEMBL582847 | 0.86 | PDE4B (0.71) | PDE4BADORA1 | |
| SCHEMBL1943837 | 0.85 | PDE4B (0.52) | PDE4BADORA1 | |
| SCHEMBL582494 | 0.85 | PDE4B (0.72) | PDE4B | |
| SCHEMBL5466164 | 0.84 | PDE4B (0.55) | PDE4BADORA1 | |
| SCHEMBL582405 | 0.84 | PDE4B (0.61) | PDE4BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124944-B1 | Pyrazolo[3,4-b]pyridine derivatives as phosphodiesterase inhibitors | RANBAXY LAB LTD (IN) | 2012-02-15 | — | — | EP | claimed |