Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | SYK | P43405 | 2/20 | 0.62 |
| ▸ | FCER2 | P06734 | 1/20 | 0.62 |
| ▸ | DHFR | P00374 | 3/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822237 | 1.00 | KMT2A (0.66) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| Acetamide SCHEMBL5822465 | 0.96 | KMT2A (0.64) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| Acetamide SCHEMBL5822463 | 0.96 | KMT2A (0.64) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL5822284 | 0.83 | KMT2A (0.75) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL5822283 | 0.83 | KMT2A (0.75) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL26434393 | 0.83 | KMT2A (0.75) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL5476060 | 0.79 | KMT2A (0.77) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL5476058 | 0.79 | KMT2A (0.77) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL5822183 | 0.79 | KMT2A (0.63) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL5822198 | 0.79 | KMT2A (0.63) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006105796-A1 | NOVEL INDOLINONE DERIVATIVES | LEO PHARMA A/S (DK) | 2006-10-12 | — | — | WO | disclosed |