Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822340 | 1.00 | PPARG (0.46) | PPARGPPARAALDH1A1PPARDFDFT1 | |
| SCHEMBL5822442 | 0.89 | PPARG (0.47) | PPARGPPARAALDH1A1PPARDNR1H2 | |
| SCHEMBL5630819 | 0.89 | PPARG (0.47) | PPARGPPARAALDH1A1PPARDNR1H2 | |
| SCHEMBL5175221 | 0.89 | PPARG (0.47) | PPARGPPARAALDH1A1PPARDNR1H2 | |
| SCHEMBL14528224 | 0.81 | PPARG (0.44) | PPARGPPARAALDH1A1PPARDNR1H2 | |
| SCHEMBL5175340 | 0.80 | PPARG (0.46) | PPARGPPARAALDH1A1PPARDNR1H2 | |
| SCHEMBL14459759 | 0.80 | PPARG (0.46) | PPARGPPARAALDH1A1PPARDNR1H2 | |
| SCHEMBL5175346 | 0.80 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL13114532 | 0.78 | PPARG (0.41) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL13114530 | 0.78 | PPARG (0.39) | PPARGPPARAPPARDNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138328-A1 | PROCESS FOR THE PRODUCTION OF ANTIDIABETIC OXAZOLIDINEDIONES | MERCK & CO., INC. (US) | 2006-12-28 | — | — | WO | disclosed |